Applicability of a semiautomated volumetric approach (5D CNS+™) for detailed antenatal reconstruction of abnormal fetal CNS anatomy.

ABSTRACT:

Background

The aim of this study was to evaluate the accuracy and reliability of a semiautomated volumetric approach (5D CNS+™) when examining fetuses with an apparent abnormal anatomy of the central nervous system (CNS).

Methods

Stored 3D volumes extracted from a cohort of > 1.400 consecutive 2nd and 3rd trimester pregnancies (range 15-36 gestational weeks) were analyzed using the semiautomatic software tool 5D CNS+™, enabling detailed reconstruction of nine diagnostic planes of the fetal brain. All 3D data sets were examined and judged for plane accuracy, the need for manual adjustment, and fetal CNS anomalies affecting successful plane reconstruction.

Results

Based on our data of 91 fetuses with structural cerebral anomalies, we were able to reveal details of a wid

SUBMITTER: Welp A 

PROVIDER: S-EPMC9438215 | biostudies-literature | 2022 Sep

REPOSITORIES: biostudies-literature