Bioinspired laminated bioceramics with high toughness for bone tissue engineering.

ABSTRACT: For the research of biomaterials in bone tissue engineering, it is still a challenge to fabricate bioceramics that overcome brittleness while maintaining the great biological performance. Here, inspired by the toughness of natural materials with hierarchical laminated structure, we presented a directional assembly-sintering approach to fabricate laminated MXene/calcium silicate-based (L-M/CS) bioceramics. Benefiting from the orderly laminated structure, the L-M/CS bioceramics exhibited significantly enhanced toughness (2.23 MPa·m^1/2) and high flexural strength (145 MPa), which were close to the mechanical properties of cortical bone. Furthermore, the L-M/CS bioceramics possessed more suitable degradability than traditional CaSiO₃ bioceramics due to the newly formed Ca

SUBMITTER: Huang J 

PROVIDER: S-EPMC9438744 | biostudies-literature | 2022

REPOSITORIES: biostudies-literature