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Bioactive natural products in COVID-19 therapy.


ABSTRACT: The devastating COVID-19 pandemic has caused more than six million deaths worldwide during the last 2 years. Effective therapeutic agents are greatly needed, yet promising magic bullets still do not exist. Numerous natural products (cordycepin, gallinamide A, plitidepsin, telocinobufagin, and tylophorine) have been widely studied and play a potential function in treating COVID-19. In this paper, we reviewed published studies (from May 2021 to April 2022) relating closely to bioactive natural products (isolated from medicinal plants, animals products, and marine organisms) in COVID-19 therapy in vitro to provide some essential guidance for anti-SARS-CoV-2 drug research and development.

SUBMITTER: Wang Z 

PROVIDER: S-EPMC9438897 | biostudies-literature | 2022

REPOSITORIES: biostudies-literature

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Bioactive natural products in COVID-19 therapy.

Wang Zhonglei Z   Wang Ning N   Yang Liyan L   Song Xian-Qing XQ  

Frontiers in pharmacology 20220819


The devastating COVID-19 pandemic has caused more than six million deaths worldwide during the last 2 years. Effective therapeutic agents are greatly needed, yet promising magic bullets still do not exist. Numerous natural products (cordycepin, gallinamide A, plitidepsin, telocinobufagin, and tylophorine) have been widely studied and play a potential function in treating COVID-19. In this paper, we reviewed published studies (from May 2021 to April 2022) relating closely to bioactive natural pro  ...[more]

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