Flashfm-ivis: interactive visualization for fine-mapping of multiple quantitative traits.

ABSTRACT:

Summary

flashfm-ivis provides a suite of interactive visualization plots to view potential causal genetic variants that underlie associations that are shared or distinct between multiple quantitative traits and compares results between single- and multi-trait fine-mapping. Unique features include network diagrams that show joint effects between variants for each trait and regional association plots that integrate fine-mapping results, all with user-controlled zoom features for an interactive exploration of potential causal variants across traits.

Availability and implementation

flashfm-ivis is an open-source software under the MIT license. It is available as an interactive web-based tool (http://shiny.mrc-bsu.cam.ac.uk/apps/flashfm-ivis/) and as an R package. Code and docume

SUBMITTER: Zhou F 

PROVIDER: S-EPMC9438951 | biostudies-literature | 2022 Sep

REPOSITORIES: biostudies-literature