Dataset Information

Flashfm-ivis: interactive visualization for fine-mapping of multiple quantitative traits.

ABSTRACT:

Summary

flashfm-ivis provides a suite of interactive visualization plots to view potential causal genetic variants that underlie associations that are shared or distinct between multiple quantitative traits and compares results between single- and multi-trait fine-mapping. Unique features include network diagrams that show joint effects between variants for each trait and regional association plots that integrate fine-mapping results, all with user-controlled zoom features for an interactive exploration of potential causal variants across traits.

Availability and implementation

flashfm-ivis is an open-source software under the MIT license. It is available as an interactive web-based tool (http://shiny.mrc-bsu.cam.ac.uk/apps/flashfm-ivis/) and as an R package. Code and documentation are available at https://github.com/fz-cambridge/flashfm-ivis and https://zenodo.org/record/6376244#.YjnarC-l2X0. Additional features can be downloaded as standalone R libraries to encourage reuse.

Supplementary information

Supplementary information are available at Bioinformatics online.

SUBMITTER: Zhou F

PROVIDER: S-EPMC9438951 | biostudies-literature | 2022 Sep

REPOSITORIES: biostudies-literature

ACCESS DATA

Publications

Flashfm-ivis: interactive visualization for fine-mapping of multiple quantitative traits.

Zhou Feng F Butterworth Adam S AS Asimit Jennifer L JL

Bioinformatics (Oxford, England) 20220901 17

<h4>Summary</h4>flashfm-ivis provides a suite of interactive visualization plots to view potential causal genetic variants that underlie associations that are shared or distinct between multiple quantitative traits and compares results between single- and multi-trait fine-mapping. Unique features include network diagrams that show joint effects between variants for each trait and regional association plots that integrate fine-mapping results, all with user-controlled zoom features for an interac ...[more]

PMID: 35792838

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Dataset Information

Flashfm-ivis: interactive visualization for fine-mapping of multiple quantitative traits.

Summary

Availability and implementation

Supplementary information

Publications

Flashfm-ivis: interactive visualization for fine-mapping of multiple quantitative traits.

Similar Datasets

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