Analysis of the Value of Serum Biomarker LBP in the Diagnosis of Spinal Tuberculosis.

ABSTRACT:

Objective

To investigate the correlation between the expression of lipopolysaccharide-binding protein (LBP) in peripheral blood of spinal tuberculosis and clinical diagnosis and to evaluate its value as a diagnostic marker of spinal tuberculosis.

Methods

In the experimental group, clinical history data and peripheral blood were collected from 100 patients with spinal tuberculosis who were admitted to the Department of Spine Surgery, General Hospital of Ningxia Medical University from May 2017 to May 2020, and peripheral blood was collected from 30 healthy volunteers in the control group. Screening of differential LBP expression by proteomics and ELISA to verify its expression in peripheral blood of spinal tuberculosis patients. t-test, Spearman analysis, linear regres

SUBMITTER: Lou C 

PROVIDER: S-EPMC9439074 | biostudies-literature | 2022

REPOSITORIES: biostudies-literature