Obstetric and perinatal outcomes in female survivors of childhood or adolescent cancer: Protocol of a meta-analysis of population-based cohort studies.

ABSTRACT:

Introduction

Approximately 80% of children, adolescents and young adults (CAYA) cancer patients are expected to fully recover and survive for five years or more. The reproductive health is a particular area of their concern. Evidence demonstrates that previous therapeutic treatments for cancer and comorbidities may have harmful effects on female fertility and delivery outcomes, which will significantly affect patient quality of life. However, these reports are heterogeneous. Therefore, the purpose of this study is to provide the up-to-date evidence on the risk of adverse obstetric and perinatal outcomes in female survivors of childhood or adolescent cancer.

Methods and analysis

This meta-analysis will be carried out and reported with adherence to the Meta-Analysis of Observa

SUBMITTER: Deng F 

PROVIDER: S-EPMC9439218 | biostudies-literature | 2022

REPOSITORIES: biostudies-literature