Clustering analysis of geriatric and acute characteristics in a cohort of very old patients on admission to ICU.

ABSTRACT:

Purpose

The biological and functional heterogeneity in very old patients constitutes a major challenge to prognostication and patient management in intensive care units (ICUs). In addition to the characteristics of acute diseases, geriatric conditions such as frailty, multimorbidity, cognitive impairment and functional disabilities were shown to influence outcome in that population. The goal of this study was to identify new and robust phenotypes based on the combination of these features to facilitate early outcome prediction.

Methods

Patients aged 80 years old or older with and without limitations of life-sustaining treatment and with complete data were recruited from the VIP2 study for phenotyping and from the COVIP study for external validation. The sequential organ fail

SUBMITTER: Mousai O 

PROVIDER: S-EPMC9439274 | biostudies-literature | 2022 Dec

REPOSITORIES: biostudies-literature