The Role of Depressive Symptoms and Physical Activity Levels in Mediating the Association Between HIV Status and Neurocognitive Functions Among Individuals Aged at Least 50 Years in China: Cross-sectional Study.

ABSTRACT:

Background

Neurocognitive impairments are prevalent among older people in China. It is more problematic among older people living with HIV.

Objective

This study aims to compare neurocognitive performance between older people living with HIV and HIV-negative controls, and to explore whether the association between HIV status and neurocognitive performance was mediated by depressive symptoms and level of physical activity.

Methods

A cross-sectional study was conducted in Yongzhou, China. All people living with HIV aged ≥50 years listed in the registry were invited. Frequency matching was used to sample HIV-negative controls from the general population according to the distribution of age, sex, and years of formal education of older people living with HIV. A total of 315

SUBMITTER: Qin P 

PROVIDER: S-EPMC9440416 | biostudies-literature | 2022 Aug

REPOSITORIES: biostudies-literature