Enhancement of Congo Red-Neomycin Resonance Rayleigh Scattering by Dodecyl Trimethyl Ammonium Bromide and its Application.

ABSTRACT: A simple, rapid, and convenient method for the determination of neomycin based on the ion association method was proposed. In Britton-Robinson buffer solution, neomycin could react with Congo red to form an ionic association, which in turn reacted with dodecyl trimethyl ammonium bromide to form a ternary ionic association. The three were combined in a 1 : 1 : 1 ratio, which significantly enhanced the resonant Rayleigh scattering intensity at 468 nm. The obtained resonant Rayleigh scattering sensor showed a linear relationship with neomycin in the range of 0.07∼1 μg·mL^-1. The limit of detection was 0.02 μg·mL^-1, and the limit of quantification was 0.037 μg·mL^-1. The experimental conditions were optimized. The method was verified based on

SUBMITTER: Zhang F 

PROVIDER: S-EPMC9440822 | biostudies-literature | 2022

REPOSITORIES: biostudies-literature