Prediction of Cerebral Palsy or Death among Preterm Infants Who Survive the Neonatal Period.

ABSTRACT:

Objective

 To assess whether neonatal morbidities evident by the time of hospital discharge are associated with subsequent cerebral palsy (CP) or death.

Study design

 This is a secondary analysis of data from a multicenter placebo-controlled trial of magnesium sulfate for the prevention of CP. The association between prespecified intermediate neonatal outcomes (n = 11) and demographic and clinical factors (n = 10) evident by the time of discharge among surviving infants (n = 1889) and the primary outcome of death or moderate/severe CP at age 2 (n = 73) was estimated, and a prediction model was created.

Results

 Gestational age in weeks at delivery (odds ratio [OR]: 0.74, 95% confidence interval [CI]: 0.67-0.83), grade III or IV intraventric

SUBMITTER: Peaceman AM 

PROVIDER: S-EPMC9440945 | biostudies-literature | 2022 May

REPOSITORIES: biostudies-literature