¹⁸F-FDG PET/CT-based radiomics nomogram could predict bone marrow involvement in pediatric neuroblastoma.

ABSTRACT:

Objective

To develop and validate an ¹⁸F-fluorodeoxyglucose (FDG) positron emission tomography/computed tomography (PET/CT)-based radiomics nomogram for non-invasively prediction of bone marrow involvement (BMI) in pediatric neuroblastoma.

Methods

A total of 133 patients with neuroblastoma were retrospectively included and randomized into the training set (n = 93) and test set (n = 40). Radiomics features were extracted from both CT and PET images. The radiomics signature was developed. Independent clinical risk factors were identified using the univariate and multivariate logistic regression analyses to construct the clinical model. The clinical-radiomics model, which integrated the radiomics signature and the independent clinical risk factors, was constructed us

SUBMITTER: Feng L 

PROVIDER: S-EPMC9440965 | biostudies-literature | 2022 Sep

REPOSITORIES: biostudies-literature