Can statins lessen the burden of virus mediated cancers?

ABSTRACT:

Background

Oncogenic viruses, including hepatitis B virus (HBV), hepatitis C virus (HCV), human papillomavirus (HPV), Epstein Barr virus (EBV), and Kaposi Sarcoma Herpes virus (KSHV) contribute to a significant proportion of the world's cancers. Given the sizeable burden of virus mediated cancers, development of strategies to prevent and/or treat these cancers is critical. While large population studies suggest that treatment with hydroxymethylglutaryl-CoA reductase inhibitors, commonly known as statins, may reduce the risk of many cancer types including HBV/HCV related hepatocellular carcinoma, few studies have specifically evaluated the impact of statin use in populations at risk for other types of virus mediated cancers.

Main body

Studies of populations with HBV and HCV s

SUBMITTER: Clark EH 

PROVIDER: S-EPMC9441070 | biostudies-literature | 2022 Sep

REPOSITORIES: biostudies-literature