Family history of breast cancer, mammographic breast density and breast cancer risk: Findings from a cohort study of Korean women.

ABSTRACT:

Background

This study investigated whether the association between family history of breast cancer in first-degree relatives and breast cancer risk varies by breast density.

Methods

Women aged 40 years and older who underwent screening between 2009 and 2010 were followed up until 2020. Family history was assessed using a self-reported questionnaire. Using Breast Imaging Reporting and Data System (BI-RADS), breast density was categorized into dense breast (heterogeneously or extremely dense) and non-dense breast (almost entirely fatty or scattered areas of fibro-glandular). Cox regression model was used to assess the association between family history and breast cancer risk.

Results

Of the 4,835,507 women, 79,153 (1.6%) reported having a family history of breast cancer

SUBMITTER: Mai Tran TX 

PROVIDER: S-EPMC9441334 | biostudies-literature | 2022 Oct

REPOSITORIES: biostudies-literature