Net clinical benefit of antithrombotic therapy for atrial fibrillation patients with stable coronary artery disease.

ABSTRACT:

Objectives

To compare the net clinical benefit of oral anticoagulant (OAC) monotherapy to OAC plus single antiplatelet therapy (SAPT) in patients with atrial fibrillation (AF) and stable coronary artery disease (CAD) at 1- and 3-year after percutaneous coronary intervention (PCI).

Background

It has not been studied whether the net clinical benefit of the antithrombotic treatment options differs depending on the elapsed time from the index PCI.

Methods

Using the Korean nationwide claims database, we included AF patients who underwent PCI from 2009 to 2019 and constructed two cohorts: 1- and 3-year after PCI. In each cohort, the baseline characteristics of two groups were balanced using propensity score weighting. Ischemic stroke, myocardial infarction, major bleeding,

SUBMITTER: Lee SR 

PROVIDER: S-EPMC9441665 | biostudies-literature | 2022

REPOSITORIES: biostudies-literature