Aberrant amplitude of low-frequency fluctuations in different frequency bands and changes after one-night positive airway pressure treatment in severe obstructive sleep apnea.

ABSTRACT:

Objective

This study was aimed to investigate the characteristics of the amplitude of low-frequency fluctuation (ALFF) at specific frequencies in severe obstructive sleep apnea (OSA) patients. A comparison was made between pre-CPAP treatment and one night after continuous positive airway pressure (CPAP) treatment.

Methods

30 severe OSA patients and 19 healthy controls (HC) were recruited. The ALFF method was used to assess the local features of spontaneous brain activity and calculated at different bands (slow-5 and slow-4). A correlation analysis was performed to evaluate the relationship between the changes of the ALFF and polysomnography data.

Results

Compared with HC, in slow-5 frequency band, OSA patients showed significantly decreased ALFF in the left inferior t

SUBMITTER: Sun Y 

PROVIDER: S-EPMC9441702 | biostudies-literature | 2022

REPOSITORIES: biostudies-literature