Lateralized brain activities in subcortical vascular mild cognitive impairment with differential Chinese medicine patterns: A resting-state functional magnetic resonance imaging study.

ABSTRACT:

Background

Subcortical vascular mild cognitive impairment (svMCI) is one of the most treatable cognitive impairments, but could be hampered by the high clinical heterogeneities. Further classification by Chinese Medicine (CM) patterns has been proved to stratify its clinical heterogeneities. It remains largely unknown of the spontaneous brain activities regarding deficiency patterns (DPs) and excess patterns (EPs) of svMCI patients based on fMRI data.

Objective

We aim to provide neuroimaging evidence of altered resting-state brain activities associated with DPs and EPs in svMCI patients.

Methods

Thirty-seven svMCI patients (PAs) and 23 healthy controls (CNs) were consecutively enrolled. All patients were categorized into either the EP group (n = 16) and the DP

SUBMITTER: Wang J 

PROVIDER: S-EPMC9441905 | biostudies-literature | 2022

REPOSITORIES: biostudies-literature