Bleeding and thrombotic complications associated with anticoagulation prior to lung transplantation: a case series.

ABSTRACT:

Background

Scarce data is available on therapeutic anticoagulation (AC) in patients undergoing pulmonary transplantation. We describe our institutional experience with AC-induced coagulopathy in recipients at the time of transplantation and evaluate its impact on posttransplant outcomes.

Methods

Records of adult patients on therapeutic AC at the time of lung transplantation from January 2014 to July 2021 were reviewed. Administration of preoperative pharmacologic reversal was assessed, with adequate reversal defined as international normalized ratio (INR) ≤1.5. We evaluated the incidence of major bleeding complications [delayed sternal closure, reoperation due to bleeding, chest tube output ≥1,500 cc, ≥4 units of packed red blood cells, ≥4 units of platelets, or ≥5 units of

SUBMITTER: Shepherd HM 

PROVIDER: S-EPMC9442523 | biostudies-literature | 2022 Aug

REPOSITORIES: biostudies-literature