Management of perioperative bleeding risk in patients on antithrombotic medications undergoing cardiac surgery-a systematic review.

ABSTRACT:

Background

Antithrombotic drugs increase the risk of bleeding, especially in patients who need urgent surgery without an adequate wash-out period. This review aims to evaluate perioperative bleeding complications in patients on dual antiplatelet therapy (DAPT) or direct-acting oral anticoagulants (DOACs) undergoing high-bleeding risk cardiovascular surgery and to present currently available potential solutions to mitigate antithrombotic therapy-related bleeding complications.

Methods

As a first step, we searched for relevant articles, over the last 10 years, in Medline (PubMed) and abstracted clinical information based on pre-defined criteria for bleeding complications. In the next step, an additional search evaluating potential solutions to mitigate bleeding complications w

SUBMITTER: Matejic-Spasic M 

PROVIDER: S-EPMC9442533 | biostudies-literature | 2022 Aug

REPOSITORIES: biostudies-literature