Elevated serum ferritin levels are associated with severity and prognosis of severe acute pancreatitis: a preliminary cohort study.

ABSTRACT:

Background

Serum ferritin (SF), as an acute-phase response protein, is used to reflect the degree of oxidative stress and systemic inflammatory responses. This study was designed to assess the effect of elevated SF levels on the severity of acute pancreatitis (AP).

Methods

From January 2013 to December 2020, 200 consecutive patients with AP were retrospectively reviewed to analyze the relationships among the etiologies of pancreatitis, the severity of the disease and SF levels. The receiver operating characteristic (ROC) curve and logistic regression analysis were used to assess whether elevated SF levels could predict the onset of organ failure in AP.

Results

92 (46%) had high SF levels (> 275 ng/ml). SF levels were not associated with the etiology of AP disease. Amo

SUBMITTER: Wang J 

PROVIDER: S-EPMC9442953 | biostudies-literature | 2022 Sep

REPOSITORIES: biostudies-literature