Mitral valve disease in ankylosing spondylitis: an autoimmune disease manifestation? A case report.

ABSTRACT:

Background

Ankylosing spondylitis (AS) is a chronic inflammatory disease of primarily the joints of the spine. In the literature, AS is known to have cardiac manifestations. Most frequently, this is aortic regurgitation. However, in rare cases also mitral valve (MV) disease is observed in AS patients. The extent and mechanism of this involvement are still unclear. We aim to describe a histologically validated case report to add understanding on this topic.

Case summary

We show the case of a 51-year-old male who suffered since his youth from back pain and uveitis, which was later diagnosed as AS. After a first presentation with combined heart valve disease, the patient recovered on cardiac medical therapy and biologic treatment for AS. Four years later, cardiac complaints wor

SUBMITTER: El Mathari S 

PROVIDER: S-EPMC9443989 | biostudies-literature | 2022 Aug

REPOSITORIES: biostudies-literature