Hormone therapy and fractures in postmenopausal women.

ABSTRACT:

Background

Fracture rates have been reported to be higher among older women living with HIV (WLWH) than HIV- women. Hormone therapy with estrogen can reduce vasomotor symptoms (VMS) associated with menopause and prevent fractures. As data are limited on the benefits of hormone therapy use in WLWH, we examined associations of hormone therapy, use and fractures.

Methods

A prospective study of 1765 (1350 WLWH and 415 HIV-) postmenopausal Women's Interagency HIV Study (WIHS) participants was performed, including self-reported hormone therapy, use and fracture data from 2003 to 2017. Proportional hazard models determined predictors of new fractures at any site or at typical fragility fracture sites (hip, spine, wrist).

Results

At the first postmenopausal visit, the median

SUBMITTER: Yin MT 

PROVIDER: S-EPMC9444941 | biostudies-literature | 2022 Oct

REPOSITORIES: biostudies-literature