A new cognitive clock matching phenotypic and epigenetic ages.
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ABSTRACT:
SUBMITTER: Krivonosov MI
PROVIDER: S-EPMC9444998 | biostudies-literature | 2022 Sep
REPOSITORIES: biostudies-literature
Publications
A new cognitive clock matching phenotypic and epigenetic ages.
Krivonosov M I MI Kondakova E V EV Bulanov N A NA Polevaya S A SA Franceschi C C Ivanchenko M V MV Vedunova M V MV
Translational psychiatry 20220906 1
Cognitive abilities decline with age, constituting a major manifestation of aging. The quantitative biomarkers of this process, as well as the correspondence to different biological clocks, remain largely an open problem. In this paper we employ the following cognitive tests: 1. differentiation of shades (campimetry); 2. evaluation of the arithmetic correctness and 3. detection of reversed letters and identify the most significant age-related cognitive indices. Based on their subsets we construc ...[more]
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