Distinct interacting cortical networks for stimulus-response and repetition-suppression.

ABSTRACT: Non-invasive studies consider the initial neural stimulus response (SR) and repetition suppression (RS) - the decreased response to repeated sensory stimuli - as engaging the same neurons. That is, RS is a suppression of the SR. We challenge this conjecture using electrocorticographic (ECoG) recordings with high spatial resolution in ten patients listening to task-irrelevant trains of auditory stimuli. SR and RS were indexed by high-frequency activity (HFA) across temporal, parietal, and frontal cortices. HFA_SR and HFA_RS were temporally and spatially distinct, with HFA_RS emerging later than HFA_SR and showing only a limited spatial intersection with HFA_SR: most HFA_SR sites did not demonstrate HFA_RS, and HFA_RS<

SUBMITTER: Eckert D 

PROVIDER: S-EPMC9445181 | biostudies-literature | 2022 Sep

REPOSITORIES: biostudies-literature