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ABSTRACT: Purpose
To investigate the risk and protective factors of dry eye disease (DED) in patients with type II diabetes mellitus (DM).Design
A retrospective cohort study using Chang- Gung research database collecting data from 2005 to 2020.Methods
Patients with type II DM were included, and those with previous ocular diseases were excluded. Ten thousand twenty nine developed DED (DED group), and 142,491 didn't (non-DED group). The possible risk and protective factors were compared and analyzed using the logistic regression model.Results
A majority of the DED group were female with significantly higher initial and average glycated hemoglobin levels, and higher incidence of diabetic neuropathy and retinopathy. In conditional logistic regression model, advanced age w
SUBMITTER: Pan LY
PROVIDER: S-EPMC9445241 | biostudies-literature | 2022
REPOSITORIES: biostudies-literature