Normal C-reactive protein in active psoriatic arthritis: results from real-world clinical practice.

ABSTRACT: The value of normal C-reactive protein (CRP) in psoriatic arthritis (PsA) is debatable. To test the hypothesis that CRP is frequently normal in contemporary real-world PsA patients, despite active disease. In this cross-sectional study, patients were divided into two groups: CRP ⩽ 0.5 mg/dl (normal) and CRP > 0.5 mg/dl (increased). Having as dependent variable the CRP status, these groups were compared for disease-related features, including composite disease activity indices [clinical Disease Activity in PSoriatic Arthritis (cDAPSA) and minimal disease activity (MDA)] and patient-reported outcomes (PROs). Agreement between CRP status and cDAPSA/MDA scores was calculated (Cohen's kappa). Data from consecutive PsA patients attending two outpatient rheumatology clinics (January 2019-June 202

SUBMITTER: Gialouri CG 

PROVIDER: S-EPMC9445451 | biostudies-literature | 2022

REPOSITORIES: biostudies-literature