Composition and diversity of gut microbiota in diabetic retinopathy.

ABSTRACT:

Objective

Diabetic retinopathy (DR) is one of the most common complications of type 2 diabetes mellitus. The current study investigates the composition, structure, and function of gut microbiota in DR patients and explores the correlation between gut microbiota and clinical characteristics of DR.

Methods

A total of 50 stool samples were collected from 50 participants, including 25 DR patients and 25 healthy controls (HCs). 16S ribosomal RNA gene sequencing was used to analyze the gut microbial composition in these two groups. DNA was extracted from the fecal samples using the MiSeq platform.

Results

The microbial structure and composition of DR patients were different from that of HCs. The microbial richness of gut microbiota in DR was higher than that of normal indiv

SUBMITTER: Bai J 

PROVIDER: S-EPMC9445585 | biostudies-literature | 2022

REPOSITORIES: biostudies-literature