New method for real-time visualization and quantitative characterization of early colorectal cancer in endoscopy: a pilot study.

ABSTRACT: Background and study aims  Endoscopic optical diagnosis is crucial to the therapeutic strategy for early gastrointestinal cancer. It accurately (> 85 %) predicts pT category based on microsurface (SP) and vascular patterns (VP). However, interobserver variability is a major problem. We have visualized and digitalized the graded irregularities based on bioinformatically enhanced quantitative endoscopic image analysis (BEE) of high-definition white-light images. Methods  In a pilot study of 26 large colorectal lesions (LCLs, mean diameter 39 mm), we retrospectively compared BEE variables with corresponding histopathology of the resected LCLs. Results  We included 10 adenomas with low-grade intraepithelial neoplasia (LGIN), nine with high-grade intraepithelial neoplasia (HGIN) and early adeno

SUBMITTER: Wagner A 

PROVIDER: S-EPMC9445923 | biostudies-literature | 2022 Aug

REPOSITORIES: biostudies-literature