Depression is differentially related to cognitive and biomarker outcomes among Mexican Americans.

ABSTRACT:

Introduction

Despite tremendous advancements in the research of Alzheimer's disease (AD), Mexican Americans, who reflect 65% of the US Hispanic community, remain severely underrepresented in research. Our data demonstrate that risk factors for, and biomarkers of, AD are different among Mexican Americans as compared with non-Hispanic whites. Here, we examined the impact of depressive symptoms on cognitive and AD-relevant biomarker outcomes among the Mexican Americans.

Methods

Data were examined from 1,633 (852 Mexican Americans and 781 non-Hispanic whites) of the Health and Aging Brain Study-Health Disparities (HABS-HD). Depression was assessed using the Geriatric Depression Scale while cognition was measured using detailed neuropsychological testing. Plasma biomarkers of Aβ4

SUBMITTER: O'Bryant SE 

PROVIDER: S-EPMC9445986 | biostudies-literature | 2022

REPOSITORIES: biostudies-literature