Ultra-high field (10.5T) diffusion-weighted MRI of the macaque brain.

ABSTRACT: Diffu0sion-weighted magnetic resonance imaging (dMRI) is a non-invasive imaging technique that provides information about the barriers to the diffusion of water molecules in tissue. In the brain, this information can be used in several important ways, including to examine tissue abnormalities associated with brain disorders and to infer anatomical connectivity and the organization of white matter bundles through the use of tractography algorithms. However, dMRI also presents certain challenges. For example, historically, the biological validation of tractography models has shown only moderate correlations with anatomical connectivity as determined through invasive tract-tracing studies. Some of the factors contributing to such issues are low spatial resolution, low signal-to-noise ratios,

SUBMITTER: Grier MD 

PROVIDER: S-EPMC9446284 | biostudies-literature | 2022 Jul

REPOSITORIES: biostudies-literature