European Stroke Organisation (ESO) guidelines on management of unruptured intracranial aneurysms.

ABSTRACT: Unruptured intracranial aneurysms (UIA) occur in around 3% of the population. Important management questions concern if and how to perform preventive UIA occlusion; if, how and when to perform follow up imaging and non-interventional means to reduce the risk of rupture. Using the Standard Operational Procedure of ESO we prepared guidelines according to GRADE methodology. Since no completed randomised trials exist, we used interim analyses of trials, and meta-analyses of observational and case-control studies to provide recommendations to guide UIA management. All recommendations were based on very low evidence. We suggest preventive occlusion if the estimated 5-year rupture risk exceeds the risk of preventive treatment. In general, we cannot recommend endovascular over microsurgical treatm

SUBMITTER: Etminan N 

PROVIDER: S-EPMC9446328 | biostudies-literature | 2022 Sep

REPOSITORIES: biostudies-literature