Screening high-risk population of persistent postpartum hypertension in women with preeclampsia using latent class cluster analysis.

ABSTRACT:

Background

A significant proportion of women with preeclampsia (PE) exhibit persistent postpartum hypertension (PHTN) at 3 months postpartum associated with cardiovascular morbidity. This study aimed to screen patients with PE to identify the high-risk population with persistent PHTN.

Methods

This retrospective cohort study enrolled 1,000 PE patients with complete parturient and postpartum blood pressure (BP) profiles at 3 months postpartum. The enrolled patients exhibited new-onset hypertension after 20 weeks of pregnancy, while those with PE superimposed upon chronic hypertension were excluded. Latent class cluster analysis (LCCA), a method of unsupervised learning in machine learning, was performed to ascertain maternal exposure clusters from eight variables and 35 subord

SUBMITTER: Li YY 

PROVIDER: S-EPMC9446580 | biostudies-literature | 2022 Sep

REPOSITORIES: biostudies-literature