Oxytocin impacts top-down and bottom-up social perception in adolescents with ASD: a MEG study of neural connectivity.

ABSTRACT:

Background

In the last decade, accumulative evidence has shown that oxytocin can modulate social perception in typically developed individuals and individuals diagnosed with autism. While several studies show that oxytocin (OT) modulates neural activation in social-related neural regions, the mechanism that underlies OT effects in ASD is not fully known yet. Despite evidence from animal studies on connections between the oxytocinergic system and excitation/inhibition neural balance, the influence of OT on oscillatory responses among individuals with ASD has been rarely examined. To bridge these gaps in knowledge, we investigated the effects of OT on both social and non-social stimuli while focusing on its specific influence on the neural connectivity between three socially related

SUBMITTER: Korisky A 

PROVIDER: S-EPMC9446859 | biostudies-literature | 2022 Sep

REPOSITORIES: biostudies-literature