A curated data resource of 214K metagenomes for characterization of the global antimicrobial resistome.

ABSTRACT: The growing threat of antimicrobial resistance (AMR) calls for new epidemiological surveillance methods, as well as a deeper understanding of how antimicrobial resistance genes (ARGs) have been transmitted around the world. The large pool of sequencing data available in public repositories provides an excellent resource for monitoring the temporal and spatial dissemination of AMR in different ecological settings. However, only a limited number of research groups globally have the computational resources to analyze such data. We retrieved 442 Tbp of sequencing reads from 214,095 metagenomic samples from the European Nucleotide Archive (ENA) and aligned them using a uniform approach against ARGs and 16S/18S rRNA genes. Here, we present the results of this extensive computational analysis and

SUBMITTER: Martiny HM 

PROVIDER: S-EPMC9447899 | biostudies-literature | 2022 Sep

REPOSITORIES: biostudies-literature