VGsim: Scalable viral genealogy simulator for global pandemic.

ABSTRACT: Accurate simulation of complex biological processes is an essential component of developing and validating new technologies and inference approaches. As an effort to help contain the COVID-19 pandemic, large numbers of SARS-CoV-2 genomes have been sequenced from most regions in the world. More than 5.5 million viral sequences are publicly available as of November 2021. Many studies estimate viral genealogies from these sequences, as these can provide valuable information about the spread of the pandemic across time and space. Additionally such data are a rich source of information about molecular evolutionary processes including natural selection, for example allowing the identification of new variants with transmissibility and immunity evasion advantages. To our knowledge, there is no fra

SUBMITTER: Shchur V 

PROVIDER: S-EPMC9447924 | biostudies-literature | 2022 Aug

REPOSITORIES: biostudies-literature