Building-level wastewater surveillance of SARS-CoV-2 is associated with transmission and variant trends in a university setting.

ABSTRACT: The University of South Carolina (UofSC) was among the first universities to include building-level wastewater surveillance of SARS-CoV-2 to complement clinical testing during its reopening in the Fall 2020 semester. In the Spring 2021 semester, 24h composite wastewater samples were collected twice per week from 10 residence halls and the on-campus student isolation and quarantine building. The isolation and quarantine building served as a positive control site. The wastewater was analyzed using RT-ddPCR for the quantification of nucleocapsid genes (N1 and N2) to identify viral transmission trends within residence halls. Log₁₀ SARS-CoV-2 RNA concentrations were compared to both new clinical cases identified in the days following wastewater collection and recovered cases returnin

SUBMITTER: Sellers SC 

PROVIDER: S-EPMC9448636 | biostudies-literature | 2022 Dec

REPOSITORIES: biostudies-literature