HCCANet: histopathological image grading of colorectal cancer using CNN based on multichannel fusion attention mechanism.

ABSTRACT: Histopathological image analysis is the gold standard for pathologists to grade colorectal cancers of different differentiation types. However, the diagnosis by pathologists is highly subjective and prone to misdiagnosis. In this study, we constructed a new attention mechanism named MCCBAM based on channel attention mechanism and spatial attention mechanism, and developed a computer-aided diagnosis (CAD) method based on CNN and MCCBAM, called HCCANet. In this study, 630 histopathology images processed with Gaussian filtering denoising were included and gradient-weighted class activation map (Grad-CAM) was used to visualize regions of interest in HCCANet to improve its interpretability. The experimental results show that the proposed HCCANet model outperforms four advanced deep learning (Re

SUBMITTER: Zhou P 

PROVIDER: S-EPMC9448811 | biostudies-literature | 2022 Sep

REPOSITORIES: biostudies-literature