Polymorphisms in chronic rhinosinusitis with nasal polyps - a systematic review.

ABSTRACT:

Introduction

Chronic rhinosinusitis with nasal polyps is a multifactorial disease with a complex pathophysiology involving multiple genetic and environmental factors.

Objective

The purpose of this work review is to focus on the importance of genetic studies in chronic rhinosinusitis with nasal polyps besides the several barriers that exists for its understanding.

Methods

A systematic review on studies of association between single nucleotide polymorphisms and chronic rhinosinusitis with nasal polyps based on a PubMed/Medline and Periódicos CAPES search of all articles published between January 2005 and January 2015 was made. The search was guided on studies containing the terms polymorphisms, rhinosinusitis, and polyps.

Results

Two studies found an association

SUBMITTER: Dinarte VRP 

PROVIDER: S-EPMC9449184 | biostudies-literature | 2017 Nov - Dec

REPOSITORIES: biostudies-literature