A chemiresistive biosensor for detection of cancer biomarker in biological fluids using CVD-grown bilayer graphene.

ABSTRACT: A chemiresistive biosensor is described for simple and selective detection of miRNA-21. We developed chemical vapor deposition (CVD) and low-damage plasma treatment (LDPT)-treated bilayer graphene composite of graphene oxide/graphene (GO/GR) for the determination of a reliable biomarker. We have successfully overcome the self-limiting growth mechanism by using CVD method to grow more than one layer of graphene on copper foil. In addition, LDPT can be used to form GO/GR structures for chemiresistive biosensor applications. Due to the direct formation of BLGR (bilayer graphene), the coupling between graphene layers is theoretically superior to that of stacked BLGR, which is also confirmed by the blue shift of the characteristic peak of graphene in Raman spectroscopy. The shift is about doubl

SUBMITTER: Govindasamy M 

PROVIDER: S-EPMC9449275 | biostudies-literature | 2022 Sep

REPOSITORIES: biostudies-literature