Identification and functional prediction of long non-coding RNAs related to skeletal muscle development in Duroc pigs.

ABSTRACT:

Objective

The growth of pigs involves multiple regulatory mechanisms, and modern molecular breeding techniques can be used to understand the skeletal muscle growth and development to promote the selection process of pigs. This study aims to explore candidate lncRNAs and mRNAs related to skeletal muscle growth and development among Duroc pigs with different average daily gain (ADG).

Methods

A total of 8 pigs were selected and divided into two groups: H group (high-ADG) and L group (low-ADG). And followed by whole transcriptome sequencing to identify differentially expressed (DE) lncRNAs and mRNAs.

Results

In RNA-seq, 703 DE mRNAs (263 up-regulated and 440 down-regulated) and 74 DE lncRNAs (45 up-regulated and 29 down-regulated) were identified. In addition, 1,418 Trans

SUBMITTER: Ma L 

PROVIDER: S-EPMC9449383 | biostudies-literature | 2022 Oct

REPOSITORIES: biostudies-literature