Estimating the effective reproduction number for heterogeneous models using incidence data.

ABSTRACT: The effective reproduction number, R(t) , plays a key role in the study of infectious diseases, indicating the current average number of new infections caused by an infected individual in an epidemic process. Estimation methods for the time evolution of R(t) , using incidence data, rely on the generation interval distribution, g(τ), which is usually obtained from empirical data or theoretical studies using simple epidemic models. However, for systems that present heterogeneity, either on the host population or in the expression of the disease, there is a lack of data and of a suitable general methodology to obtain g(τ). In this work, we use mathematical models to bridge this gap. We present a general methodology for obtaining explicit expressions of the reproduc

SUBMITTER: Jorge DCP 

PROVIDER: S-EPMC9449464 | biostudies-literature | 2022 Sep

REPOSITORIES: biostudies-literature