A novel electrochemical immunosensor based on PdAgPt/MoS₂ for the ultrasensitive detection of CA 242.

ABSTRACT: Dynamic monitoring of tumor markers is an important way to the diagnosis of malignant tumor, evaluate the therapeutic effect of tumor and analyze the prognosis of cancer patients. As a tumor marker of digestive tract, CA242 is often used to Assess the therapeutic effect of colorectal cancer and pancreatic cancer. In this study, immunosensor technology was used to detect CA242. PdAgPt nanocomposites, which have great advantages in biocompatibility, electrical conductivity and catalytic properties, were prepared by hydrothermal synthesis method. The prepared PdAgPt nanocomposites were loaded onto the surface of molybdenum disulfide (MoS₂) with large surface area, and the new nanocomposites were synthesized. Using PdAgPt/MoS₂ as signal amplification platform, the label-f

SUBMITTER: Cao L 

PROVIDER: S-EPMC9449583 | biostudies-literature | 2022

REPOSITORIES: biostudies-literature