Zr(HSO₄)₄: Green, efficient and reusable catalyst for one-pot synthesis of 1,8-dioxooctahydroxanthene under solvent-free conditions.

ABSTRACT: Many methods have been used to synthesize xanthene derivatives using different catalysts. However, some of these methodologies have not been entirely satisfactory. Most of the mentioned methods have disadvantages such as low yields, prolonged reaction times, harsh reaction conditions and the requirement of expensive catalysis and use of toxic organic solvent. In this research, a green and highly efficient procedure for the one-pot synthesis of 1,8-dioxo-octahydro-xanthenes has been developed. Zr(HSO₄)₄ catalyst was used as an efficient and recoverable catalyst for synthesis of 1,8-dioxo-octahydro-xanthene derivatives via cyclocondensation of dimedone and aromatic aldehydes in solvent-free conditions. There are no examples of the use of Zr(HSO₄)₄

SUBMITTER: Pourshamsian K 

PROVIDER: S-EPMC9450119 | biostudies-literature | 2022

REPOSITORIES: biostudies-literature