Association between hamstring coactivation during isokinetic quadriceps strength testing and knee cartilage worsening over 24 months.

ABSTRACT:

Objective

This study aimed to determine longitudinal associations, including sex-specific differences, between greater knee flexor antagonist coactivation and worsening cartilage morphology in knees with or at risk for osteoarthritis (OA).

Design

Baseline measurements were collected at the 60-month visit of a longitudinal osteoarthritis study following community-dwelling participants (MOST). Knee flexor and extensor muscle activity were measured with surface electromyography during a maximal isokinetic knee extension task. MRI analyzed knee cartilage morphology at baseline and 24-month follow-up. Multivariable adjusted logistic regression models were used to assess associations between coactivation level and cartilage morphology worsening.

Results

Analysis of 373 wome

SUBMITTER: Murphy MT 

PROVIDER: S-EPMC9450915 | biostudies-literature | 2022 Jun

REPOSITORIES: biostudies-literature