Risk stratification of patients with acute respiratory distress syndrome complicated with sepsis using lactate trajectories.

ABSTRACT:

Background

No consensus has been reached on an optimal blood lactate evaluation system although several approaches have been reported in the literature in recent years. A group-based trajectory modeling (GBTM) method could better stratify patients with acute respiratory distress syndrome (ARDS) complicated with sepsis in the intensive care unit (ICU).

Patients and methods

760 patients from the comprehensive ICU of Tianjin Medical University General Hospital with ARDS complicated with sepsis were eligible for analysis. Serial serum lactate levels were measured within 48 h of admission. In addition to the GBTM lactate groups, the initial lactate, peak lactate level, the area under the curve of serial lactate (lactate AUC), and lactate clearance were also considered for compari

SUBMITTER: Zhang H 

PROVIDER: S-EPMC9451114 | biostudies-literature | 2022 Sep

REPOSITORIES: biostudies-literature