Relationship between viral load and symptoms in children infected with SARS-CoV-2.

ABSTRACT:

Background

The purpose of this study is to evaluate the association between SARS-CoV-2 viral load in respiratory secretions of infected children and signs/symptoms of COVID-19.

Methods

We reported the clinical characteristics of SARS-CoV-2-infected children during the study period. We compared viral load for several clinical variables, performed a predictive linear regression analysis to identify signs and symptoms significantly associated with viral load, and searched for discriminant viral load thresholds for symptomatic versus asymptomatic infections based on receiver-operating characteristics.

Results

A total of 570 patients were included. The median age was 4.75 years. Comparison of CT values by dichotomous variable showed higher viral loads in children with feve

SUBMITTER: Roversi M 

PROVIDER: S-EPMC9451120 | biostudies-literature | 2022 Sep

REPOSITORIES: biostudies-literature