Tibiofemoral knee osteoarthritis progresses symmetrically by knee compartment in the GOGO cohort.

ABSTRACT:

Objective

To evaluate the degree of symmetry of knee osteoarthritis (OA) structural severity and progression of participants with a mean follow-up time of 3.8 years.

Design

Participants from the Genetics of Generalized Osteoarthritis (GOGO) study (n = 705) were selected on the basis of radiographic evidence of OA in at least 1 knee, availability of radiographs at baseline and follow-up, and no history of prior knee injury or surgery. Incidence and progression of osteoarthritis were determined by radiographic Kellgren-Lawrence (KL) grade; compartmental OA progression was determined by change in joint space width of lateral and medial tibiofemoral compartments. Total OA progression was the sum of change in KL grade of both knees.

Results

Compared with left knees, right

SUBMITTER: Alexander LC 

PROVIDER: S-EPMC9451142 | biostudies-literature | 2022 Sep

REPOSITORIES: biostudies-literature