Flow Diversion in the Treatment of Intracranial Aneurysms: A Pragmatic Randomized Care Trial.

ABSTRACT:

Background and purpose

Flow diversion is a recent endovascular treatment for intracranial aneurysms. We compared the safety and efficacy of flow diversion with the alternative standard management options.

Materials and methods

A parallel group, prerandomized, controlled, open-label pragmatic trial was conducted in 3 Canadian centers. The trial included all patients considered for flow diversion. A Web-based platform 1:1 randomly allocated patients to flow diversion or 1 of 4 alternative standard management options (coiling with/without stent placement, parent vessel occlusion, surgical clipping, or observation) as prespecified by clinical judgment. Patients ineligible for alternative standard management options were treated with flow diversion in a registry. The primary safe

SUBMITTER: Raymond J 

PROVIDER: S-EPMC9451626 | biostudies-literature | 2022 Sep

REPOSITORIES: biostudies-literature