Drug-induced comorbidities in patients with sarcoidosis.

ABSTRACT:

Purpose of review

Sarcoidosis is a chronic multisystemic inflammatory disease of unknown aetiology with a wide range of highly variable clinical manifestations and unpredictable disease course. Sarcoidosis patients may present with specific organ-related symptoms involving functional impairments, and less specific symptoms. The decision whether and when to treat a sarcoidosis patient with pharmacotherapy depends on two major factors: risk of organ failure and/or death and impairment of quality of life. This decision is complex and not standardized.

Recent findings

Glucocorticoids (GCs) are recommended as initial treatment, when needed. Subsequent GC-sparing alternatives frequently follow. Comorbidities or adverse drug reactions (ADRs) from drugs used in sarcoidosis treatment

SUBMITTER: Drent M 

PROVIDER: S-EPMC9451917 | biostudies-literature | 2022 Sep

REPOSITORIES: biostudies-literature