Anticoagulation in COVID-19 patients - An updated systematic review and meta-analysis.

ABSTRACT:

Background

Thromboembolic events are common complications of COVID-19. Clinical study results on safety and efficacy of anticoagulation in COVID-19 are controversial.

Material and methods

This report updates our systematic review and random-effects meta-analysis on randomized controlled trials (RCTs) comparing standard prophylactic anticoagulation and intermediate or therapeutic anticoagulation in COVID-19 patients. We searched eligible studies for the update up to 4 February 2022 by weekly monitoring of RCTs in the Cochrane COVID-19 Study Register. Certainty of evidence was assessed using GRADE (Grading of Recommendations Assessment, Development and Evaluation).

Results

For this update we included five new trials; a total of 13 RCTs with 7364 patients. Certainty of e

SUBMITTER: Reis S 

PROVIDER: S-EPMC9451936 | biostudies-literature | 2022 Nov

REPOSITORIES: biostudies-literature