Determination of the extent of dissection in early gastric cancer based on lymph node station power index.

ABSTRACT:

Background

The relative prognostic value of each lymph node (LN) station remains undefined in the treatment of gastric cancer. This study aimed to develop a new method to evaluate LN station ranking and define the optimal extent of lymphadenectomy for early gastric cancer.

Methods

Clinical and histopathological information from patients who underwent curative gastrectomy with lymphadenectomy between 1989 and 2018 was reviewed. The LN station power index (LNPI) of each station was estimated using a LN retrieval frequency and the 5-year overall survival of patients with absence of LN at each station. External validation was conducted to evaluate the relevance of the LNPI.

Results

A training set was developed from examination of 7009 patient records. For most nodal stati

SUBMITTER: Jeon CH 

PROVIDER: S-EPMC9452541 | biostudies-literature | 2022 Sep

REPOSITORIES: biostudies-literature